Marbofloxacin EP Impurity B CAS 115551-41-2
| CAS No. | 115551-41-2 |
| Molecular Formula | C12H8F2N2O4 |
| Molecular Weight | 282.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Marbofloxacin EP Impurity B (CAS 115551-41-2, C12H8F2N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Marbofloxacin EP Impurity B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 282.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Marbofloxacin EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8F2N2O4 |
| Molecular Weight | 282.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Marbofloxacin Standards
- Marbofloxacin Impurity 9 (CAS 100276-67-3)
- Marbofloxacin EP Impurity A (CAS 115551-40-1)
- Marbofloxacin EP Impurity D (CAS 117380-92-4)
- Marbofloxacin EP Impurity C (CAS 100276-37-7)
- Marbofloxacin (CAS 115550-35-1)
- Marbofloxacin-d8 (CAS 1185053-37-5)
- Marbofloxacin Impurity 10 (CAS CATO-C4X-180010)
- Marbofloxacin EP Impurity F (CAS 194023-72-8)
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