Marbofloxacin EP Impurity F CAS 194023-72-8
| CAS No. | 194023-72-8 |
| Molecular Formula | C17H19FN4O5 |
| Molecular Weight | 378.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 378.35 g/mol gives Marbofloxacin EP Impurity F distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Marbofloxacin EP Impurity F (CAS 194023-72-8) is a certified pharmaceutical impurity reference standard with the molecular formula C17H19FN4O5 and a molecular weight of 378.35 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Marbofloxacin EP Impurity F is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H19FN4O5 |
| Molecular Weight | 378.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Marbofloxacin Standards
- Marbofloxacin EP Impurity E (CAS 2249835-04-7)
- Marbofloxacin Impurity 10 (CAS CATO-C4X-180010)
- Marbofloxacin-d8 (CAS 1185053-37-5)
- Marbofloxacin (CAS 115550-35-1)
- Marbofloxacin EP Impurity C (CAS 100276-37-7)
- Marbofloxacin EP Impurity D (CAS 117380-92-4)
- Marbofloxacin EP Impurity B (CAS 115551-41-2)
- Marbofloxacin Impurity 9 (CAS 100276-67-3)
Recommended Standards
- 1,1-BIS(3-AMINO-4-HYDROXYPHENYL)-2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHANE 2,2'-DIAMINO-4,4'-(PERFLUOROPROPANE-2,2-DIYL)DIPHENOL 2,2-BIS(3-AMINO-4-HYDROPHENYL) HEXAFLUOROPROPANE 2,2-BIS(3-AMINO-4-HYDROXYPHENYL)HEXAFLUOROPROPANE 2,2-BIS[4-HYDROXYL-3-AMINOPHENYL]HEXAFLUOROPROPANE 2-AMINO-4-[1-(3-AMINO-4-HYDROXYPHENYL)-2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHYL]PHENOL 4,4'-(1,1,1,3,3,3-HEXAFLUOROPROPANE-2,2-DIYL)BIS(2-AMINOPHENOL) 4,4'-(HEXAFLUOROISOPROPYLIDENE)BIS(2-AMINOPHENOL) 4,4'-(PERFLUOROPROPANE-2,2-DIYL)BIS(2-AMINOPHENOL) 83558-87-6 BHAPFP BIS-AP-AF EF10125 (CAS 83558-87-6)
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