n-(2,4-Difluorophenyl)-2-hydroxyacetamide CAS 1155533-58-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1155533-58-6
Molecular FormulaC8H7F2NO2
Molecular Weight187.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

n-(2,4-Difluorophenyl)-2-hydroxyacetamide CAS 1155533-58-6 chemical structure

Description

As a certified reference material (CRM), n-(2,4-Difluorophenyl)-2-hydroxyacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

n-(2,4-Difluorophenyl)-2-hydroxyacetamide (CAS 1155533-58-6), molecular formula C8H7F2NO2 and molecular weight 187.14 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of n-(2,4-Difluorophenyl)-2-hydroxyacetamide (C8H7F2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC8H7F2NO2
Molecular Weight187.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms1

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