2-[2-(3,4-difluorophenyl)-1,3-thiazol-4-yl]acetic acid CAS 1156584-75-6

Description

The molecular framework of 2-[2-(3,4-difluorophenyl)-1,3-thiazol-4-yl]acetic acid (C11H7F2NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

2-[2-(3,4-difluorophenyl)-1,3-thiazol-4-yl]acetic acid (CAS 1156584-75-6), molecular formula C11H7F2NO2S and molecular weight 255.24 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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