1-(4-Fluorophenyl)-3-((2-hydroxyethyl)thio)propan-2-one CAS 1157308-64-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Fluorophenyl)-3-((2-hydroxyethyl)thio)propan-2-one.

CATO supplies 1-(4-Fluorophenyl)-3-((2-hydroxyethyl)thio)propan-2-one (CAS 1157308-64-9), a certified reference material (molecular formula C11H13FO2S, MW 228.28 g/mol) for analytical method development and quality control.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 1-(4-Fluorophenyl)-3-((2-hydroxyethyl)thio)propan-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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