Ticagrelor impurity 161 CAS 1157692-93-7
| CAS No. | 1157692-93-7 |
| Molecular Formula | C9H9F2N |
| Molecular Weight | 169.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ticagrelor impurity 161 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Ticagrelor impurity 161 (CAS 1157692-93-7), a pharmacopoeial impurity reference standard (molecular formula C9H9F2N, MW 169.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, Ticagrelor impurity 161 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 169.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H9F2N |
| Molecular Weight | 169.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 121 (CAS 1006614-49-8)
- Ticagrelor Impurity 113 (CAS 1156575-52-8)
- Ticagrelor impurity 156 (CAS 1415905-52-0)
- Ticagrelor impurity 159 (CAS 1511636-19-3)
- Ticagrelor impurity 160 (CAS 220352-50-1)
- Ticagrelor Impurity 20 (CAS 633312-86-4)
- Ticagrelor impurity 22 (CAS 1459719-81-3)
- Ticagrelor Impurity 57 (CAS 1427524-53-5)
Recommended Standards
- Ticagrelor Impurity N33 (CAS 1345413-20-8)
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Why CATO?
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