(E)-2-(3,4-difluorophenyl)ethene-1-sulfonyl chloride CAS 1158108-22-5

Description

Compared with other compounds in its class, the molecular weight of 238.64 g/mol gives (E)-2-(3,4-difluorophenyl)ethene-1-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(E)-2-(3,4-difluorophenyl)ethene-1-sulfonyl chloride (CAS 1158108-22-5), molecular formula C8H5ClF2O2S and molecular weight 238.64 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (E)-2-(3,4-difluorophenyl)ethene-1-sulfonyl chloride (C8H5ClF2O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (E)-2-(3,4-difluorophenyl)ethene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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