2-Fluoro-3-(trifluoromethoxy)phenylacetic acid CAS 1159512-61-4
| CAS No. | 1159512-61-4 |
| Molecular Formula | C9H6F4O3 |
| Molecular Weight | 238.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Fluoro-3-(trifluoromethoxy)phenylacetic acid.
CATO supplies 2-Fluoro-3-(trifluoromethoxy)phenylacetic acid (CAS 1159512-61-4), a certified reference material (molecular formula C9H6F4O3, MW 238.14 g/mol) for analytical method development and quality control.
The molecular framework of 2-Fluoro-3-(trifluoromethoxy)phenylacetic acid (C9H6F4O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Fluoro-3-(trifluoromethoxy)phenylacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6F4O3 |
| Molecular Weight | 238.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Fluoro Standards
- Methyl 4-fluoro-3-(trifluoromethoxy)benzoate (CAS 1012869-32-7)
- 3-Fluoro-4-(2,2,2-trifluoroethoxy)benzoic acid (CAS 1020998-55-3)
- 2-(5-Fluoro-2-(trifluoromethoxy)phenyl)acetic acid (CAS 1092460-92-8)
- 2-(2-Fluoro-3-(trifluoromethyl)phenyl)-2-hydroxyacetic acid (CAS 1214323-18-8)
- 2-(3-Fluoro-5-(trifluoromethyl)phenyl)-2-hydroxyacetic acid (CAS 1214341-24-8)
- 2-(3-Fluoro-4-(trifluoromethyl)phenyl)-2-hydroxyacetic acid (CAS 1214343-86-8)
- 2-(2-Fluoro-4-(trifluoromethoxy)phenyl)acetic acid (CAS 1240256-95-4)
- 2-(4-Fluoro-2-(trifluoromethoxy)phenyl)acetic acid (CAS 1323966-19-3)
Recommended Standards
- 2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine-6,7-diamine (CAS 110968-70-2)
- Methyl 4-(difluoromethoxy)-2,6-difluorobenzoate (CAS 1040723-82-7)
- (R)-2-amino-2-(3-fluoro-2-(trifluoromethyl)pyridin-4-yl)acetic acid (CAS 1269914-11-5)
- 4-(1,1,2,2-Tetrafluoroethoxy)benzoic acid (CAS 10009-25-3)
- Triisopropyl[(trimethylsilyl)ethynyl]silane (CAS 107474-02-2)
- 2-((2-Benzoylphenyl)amino)propanoic acid (CAS 76477-50-4)
- 2-Chloro-3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 2283377-62-6)
- (E)-3-(4-((2-chloro-6-fluorobenzyl)oxy)phenyl)acrylic acid (CAS 400825-72-1)
- 5-Methyl-3-propyl-3-(pyridin-2-yl)dihydrofuran-2(3H)-one (CAS 71824-64-1)
- (3-Chloro-4-(3-(4-methylpiperidin-1-yl)propoxy)phenyl)boronic acid (CAS 1704081-78-6)
- N-Ethyl-2,5-dimethoxyaniline (CAS 42487-19-4)
- 4-(3-Fluoro-4-methoxyphenyl)pyrrolidine-3-carboxylic acid (CAS 1466950-14-0)
- 4-(3,4-Dihydro-2h-1,5-benzodioxepine-7-sulfonamido)butanoic acid (CAS 781626-94-6)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
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