2-(5-Ethyl-2-thienyl)-6,8-dimethylquinoline-4-carbonyl chloride CAS 1160254-83-0
| CAS No. | 1160254-83-0 |
| Molecular Formula | C18H16ClNOS |
| Molecular Weight | 329.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(5-Ethyl-2-thienyl)-6,8-dimethylquinoline-4-carbonyl chloride is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(5-Ethyl-2-thienyl)-6,8-dimethylquinoline-4-carbonyl chloride (CAS 1160254-83-0), molecular formula C18H16ClNOS and molecular weight 329.84 g/mol, is a CATO reference standard with documented purity and traceability.
2-(5-Ethyl-2-thienyl)-6,8-dimethylquinoline-4-carbonyl chloride (C18H16ClNOS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(5-Ethyl-2-thienyl)-6,8-dimethylquinoline-4-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16ClNOS |
| Molecular Weight | 329.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 2-(5-Ethyl-2-thienyl)-7,8-dimethylquinoline-4-carbonyl chloride (CAS 1160261-43-7)
- 5-[7-(2-Thienyl)-2,1,3-benzothiadiazol-4-yl]-2-thiophenecarboxaldehyde (CAS 1042440-26-5)
- 2-Thienyl-N,N-bis(2-thienylmethylene)methanediamine (CAS 314280-18-7)
- 2-[(3-Methyl-2-thienyl)methylene]-3-phenyl-1-indanone (CAS 337921-68-3)
- Methyl 3-(2-thienyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate (CAS 478048-35-0)
- 2-(5-Ethyl-2-thienyl)-6-methylquinoline-4-carbonyl chloride (CAS 1160253-35-9)
- 2-(5-Ethyl-2-thienyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160254-05-6)
- 1171976-97-8 4-(2-Thienyl)-5,6,8,9-tetrahydro-4H,7H-cyclopenta[4,5]thieno[3,2-f]pyrrolo[1,2-a][1,4]diazepine MFCD14282071 (CAS 1171976-97-8)
Recommended Standards
- Ethyl 2-[(2-chloropropanoyl)amino]-5,6,7,8-tetra-hydro-4H-cyclohepta[b]thiophene-3-carboxylate (CAS 1092289-44-5)
- 6-Ethyl-2-(5-ethyl-2-thienyl)quinoline-4-carbonyl chloride (CAS 1160257-18-0)
- 5-Chloro-N-(5-isopropyl-1,3,4-thiadiazol-2-yl)-2-(methylthio)pyrimidine-4-carboxamide (CAS 879930-44-6)
- 5-Chloro-2-(methylthio)-N-(5-propyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide (CAS 838400-01-4)
- Dopamine Impurity 14 (CAS 217657-34-6)
- 1-(2,5-Dimethylphenyl)propan-2-one (CAS 53291-89-7)
- 3-Hydrazinyl-5,7-dimethyl-2H-indol-2-one (CAS 325833-87-2)
- 2-Thiomethyl-4-thiomorpholinomethyl benzophenone (CAS 898782-55-3)
- Niraparib Impurity 6 (CAS 1369926-38-4)
- N-methylquinolin-3-amine (CAS 343330-71-2)
- (R)-tert-butyl 3-((6-bromo-5-cyano-3-ethylpyrazin-2-yl)oxy)pyrrolidine-1-carboxylate (CAS 2444046-02-8)
- Methyl 4-(2-aminoethyl)-6-methoxypicolinate (CAS 1393569-36-2)
- Lead niobium potassium oxide (CAS 12372-45-1)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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