8-Chloro-2-(4-isopropylphenyl)quinoline-4-carbonyl chloride CAS 1160256-10-9
| CAS No. | 1160256-10-9 |
| Molecular Formula | C19H15Cl2NO |
| Molecular Weight | 344.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 8-Chloro-2-(4-isopropylphenyl)quinoline-4-carbonyl chloride (CAS 1160256-10-9), a certified reference material (molecular formula C19H15Cl2NO, MW 344.23 g/mol) for analytical method development and quality control.
The molecular framework of 8-Chloro-2-(4-isopropylphenyl)quinoline-4-carbonyl chloride (C19H15Cl2NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Chloro-2-(4-isopropylphenyl)quinoline-4-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15Cl2NO |
| Molecular Weight | 344.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 7-Chloro-2-(4-ethylphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160256-04-1)
- 8-Chloro-2-(4-propylphenyl)quinoline-4-carbonyl chloride (CAS 1160256-06-3)
- 7-Chloro-2-(3,4-dimethylphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160256-40-5)
- 7-Chloro-2-(2,5-dimethylphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160256-44-9)
- 7-Chloro-2-(2,4-dimethylphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160256-48-3)
- 7-Chloro-3,8-dimethyl-2-(4-methylphenyl)quinoline-4-carbonyl chloride (CAS 1160257-02-2)
- 6-Chloro-2-(4-propylphenyl)quinoline-4-carbonyl chloride (CAS 1160263-17-1)
- 6-Chloro-2-(4-isopropylphenyl)quinoline-4-carbonyl chloride (CAS 1160263-18-2)
Recommended Standards
- N'-((2,4-Dichloropyridin-3-yl)methylene)-4-methylbenzenesulfonohydrazide (CAS 2586233-02-3)
- Methyl 3-(((2-(2,4-dichlorophenyl)hydrazinyl)methylene)amino)thiophene-2-carboxylate (CAS 866051-39-0)
- Ethyl 2-amino-6-bromo-7-ethoxybenzo[b]thiophene-3-carboxylate (CAS 299962-53-1)
- 2-Amino-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-5-fluorobenzamide (CAS 63497-94-9)
- 2-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate (CAS 805304-35-2)
- (Z)-1-(1H-pyrrol-2-yl)ethan-1-one oxime (CAS 954118-47-9)
- 1-(3,5-Dichlorobenzenesulfonyl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine (CAS 478077-47-3)
- 2-ethyloxolane-3-carboxylic acid (CAS 153756-61-7)
- Estriol EP Impurity H (CAS 566-76-7)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-(trifluoromethoxy)pyridin-4-amine (CAS 1804433-22-4)
- 4-Methyl-6-(piperazin-1-yl)pyrimidin-2-amine (CAS 32705-71-8)
- 6-Fluoro-4-iodopyridine-2-sulfonyl chloride (CAS 1393538-76-5)
- Paricalcitol Impurity 15 (CAS 100858-25-1)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
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