Aminophylline EP Impurity D CAS 116131-08-9
| CAS No. | 116131-08-9 |
| Molecular Formula | C6H10N4O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Aminophylline EP Impurity D (CAS 116131-08-9), a pharmacopoeial impurity reference standard (molecular formula C6H10N4OHCl, MW 190.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C6H10N4OHCl, Aminophylline EP Impurity D contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 190.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Aminophylline EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10N4O HCl |
| Molecular Weight | 190.63 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Aminophylline Standards
Recommended Standards
- Iptacopan Impurity 7 (CAS 1644670-76-7)
- Paliperidone Impurity 160 (CAS CATO-C4X-1724160)
- Rivastigmine impurity 35 (CAS CATO-C4X-138435)
- 2-Methyl-4,5,6,7-tetrahydrobenzo[d]thiazol-4-amine dihydrochloride (CAS 1255717-68-0)
- 5-(Chloromethyl)-2-methoxy-1,3-dimethylbenzene (CAS 32692-27-6)
- 2-Cyano-2-(hydroxyimino)acetic Acid (CAS 78325-18-5)
- (6S)-1,4-oxazepan-6-ol (CAS 1373232-31-5)
- (S)-tert-Butyl 3-((2-chloro-5-fluoropyrimidin-4-yl)amino)piperidine-1-carboxylate (CAS 1259009-67-0)
- Ethyl 2-aminooxazole-4-carboxylate (CAS 177760-52-0)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com