【禁售品】Aminophylline EP Impurity A(Pentoxifylline EP Impurity F) CAS 58-08-2

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.58-08-2
Molecular FormulaC8H10N4O2
Molecular Weight194.19 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

【禁售品】Aminophylline EP Impurity A(Pentoxifylline EP Impurity F) CAS 58-08-2 chemical structure

Description

The occurrence of 【禁售品】Aminophylline EP Impurity A(Pentoxifylline EP Impurity F) is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

As a process- or degradation-related impurity, 【禁售品】Aminophylline EP Impurity A(Pentoxifylline EP Impurity F) (CAS 58-08-2, C8H10N4O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Structurally, 【禁售品】Aminophylline EP Impurity A(Pentoxifylline EP Impurity F) (C8H10N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 194.19 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), 【禁售品】Aminophylline EP Impurity A(Pentoxifylline EP Impurity F) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H10N4O2
Molecular Weight194.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms4

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