Mosapride Impurity 1 CAS 1161443-73-7
| CAS No. | 1161443-73-7 |
| Molecular Formula | C21H25ClFN3O4 |
| Molecular Weight | 437.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 437.89 g/mol gives Mosapride Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Mosapride Impurity 1 (CAS 1161443-73-7, C21H25ClFN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H25ClFN3O4, Mosapride Impurity 1 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 437.89 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H25ClFN3O4 |
| Molecular Weight | 437.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Mosapride Standards
- Mosapride Impurity 40 (CAS CATO-C4X-104440)
- Mosapride Impurity 1 (CAS 2196138-12-0)
- Mosapride-d5 (CAS 1246820-66-5)
- Mosapride Impurity 72 (CAS CATO-C4X-104472)
- Mosapride impurity 52 (CAS CATO-C4X-104552)
- Mosapride (CAS 112885-41-3)
- Mosapride Impurity 36 (CAS 112886-56-3)
- Mosapride Impurity 11 (CAS CATO-C4X-104411)
Recommended Standards
- 3-Chloro-N-(4-((trifluoromethyl)thio)phenyl)naphtho[1,2-b]thiophene-2-carboxamide (CAS 1024316-70-8)
- SP 2509 (CAS 1423715-09-6)
- Tivozanib Impurity 8 (CAS CATO-C4X-34008)
- Phenyl 2-((2-((4-chlorophenyl)amino)-2-oxoethyl)thio)-1H-benzo[d]imidazole-1-carboxylate (CAS 845879-37-0)
- Ozenoxacin Impurity 64 (CAS CATO-C4X-279664)
- Micafungin Impurity 15 (CAS CATO-C4X-169515)
- Eltrombopag Impurity N1 Chloride (CAS 69457-08-5)
- 2-Amino-N,N-diethyl-3-phenylpropanamidehydrochloride (CAS 1236267-49-4)
- 4-Pyridinedialdoxime (CAS 22866-50-8)
- 5-Bromo-6-methoxy-3-nitropicolinonitrile (CAS 2763158-05-8)
- 3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-(4-methylbenzenesulfonyl)-1H-pyrazole (CAS 477710-94-4)
- 1-Propylcytosine (CAS 22919-46-6)
- (Z)-[(4-Methoxyphenyl)methyl](oxido)(phenylmethylidene)azanium (CAS 55606-35-4)
- Galanin Message Associated Peptide (1-41) amide trifluoroacetate salt (CAS 132699-74-2)
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