Eltrombopag Impurity N1 Chloride CAS 69457-08-5
| CAS No. | 69457-08-5 |
| Molecular Formula | C8H9N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 168.62 g/mol gives Eltrombopag Impurity N1 Chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Eltrombopag Impurity N1 Chloride (CAS 69457-08-5) is a certified pharmaceutical impurity reference standard with the molecular formula C8H9N2Cl and a molecular weight of 168.62 g/mol.
Structurally, Eltrombopag Impurity N1 Chloride (C8H9N2Cl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 168.62 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Eltrombopag Impurity N1 Chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9N2 Cl |
| Molecular Weight | 168.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Eltrombopag Standards
- Eltrombopag Impurity 39 (CAS 103966-66-1)
- Eltrombopag Impurity 89 (CAS 1097777-60-0)
- Eltrombopag Impurity 94 (CAS 1176777-76-6)
- Eltrombopag Impurity 102 (CAS 118048-94-5)
- Eltrombopag-13C4 (CAS 1217230-31-3)
- Eltrombopag Methyl Ester (CAS 1246929-01-0)
- Eltrombopag Impurity 4 (CAS 1246929-02-1)
- Eltrombopag Impurity 34 (CAS 13073-25-1)
Recommended Standards
- Ruxolitinib Impurity 237 (CAS CATO-C4X-2058237)
- Pefloxacin EP Impurity H (CAS 106847-40-9)
- Polidocanol Impurity 1 (CAS CATO-C4X-29441)
- 5-(2-(4-Chlorophenyl)-2-oxoethylidene)-2-imino-3-(o-tolyl)oxazolidin-4-one (CAS 122975-87-5)
- [(4-Methyl-1,3-benzoxazol-2-yl)methyl]amine hydrochloride (CAS 1255717-38-4)
- Sodium 2-(3-fluoropyridin-2-yl)acetate (CAS 1643136-66-6)
- 2-Chloro-9,10-diphenyl-9,10-dihydroacridin-9-ol (CAS 6321-78-4)
- (2-(Thiophen-2-yl)cyclopropyl)methanamine (CAS 1226016-59-6)
- Difluoro(2,3,4-trifluorophenyl)methyl octanoate (CAS 21635-03-0)
- D-[Val]10-Semaglutide (CAS CATO-CPTD788630)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com