5-Chloro-N-[2-oxo-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-2-thiophenecarboxamide CAS 1161719-52-3
| CAS No. | 1161719-52-3 |
| Molecular Formula | C18H18ClN3O4S |
| Molecular Weight | 407.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 407.87 g/mol gives 5-Chloro-N-[2-oxo-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-2-thiophenecarboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-N-[2-oxo-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-2-thiophenecarboxamide (CAS 1161719-52-3), molecular formula C18H18ClN3O4S and molecular weight 407.87 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-N-[2-oxo-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-2-thiophenecarboxamide (C18H18ClN3O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O4S |
| Molecular Weight | 407.87 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 4-Methyl-[2,3'-bipyridine]-5'-carbaldehyde (CAS 1346686-70-1)
- Cefcapene Impurity 12 (CAS 3025716-46-2)
- 5-Bromo-2-cyclopropylisoindoline (CAS 1392147-82-8)
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- 2-(4-(4-Fluorophenyl)-2-methylthiazol-5-yl)acetic acid 568543-71-5 8325AB C12H10FNO2S (CAS 568543-71-5)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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