5-fluoro-1-methyl-indole CAS 116176-92-2
| CAS No. | 116176-92-2 |
| Molecular Formula | C9H8FN |
| Molecular Weight | 149.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 149.16 g/mol gives 5-fluoro-1-methyl-indole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-fluoro-1-methyl-indole (CAS 116176-92-2) is a high-purity analytical reference standard with the molecular formula C9H8FN and a molecular weight of 149.16 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 5-fluoro-1-methyl-indole is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 149.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-fluoro-1-methyl-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8FN |
| Molecular Weight | 149.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related fluoro Standards
- 5-Fluoro-6-methyl-1H-indole (CAS 1000343-16-7)
- 2-(4-Fluoro-3-methylphenyl)acetonitrile (CAS 1000548-41-3)
- 6-Fluoro-3-methyl-1H-indole (CAS 1011484-23-3)
- 5-Fluoro-7-methyl-1H-indole (CAS 1082041-52-8)
- 2-Fluoro-α-methylbenzeneacetonitrile (CAS 1096308-40-5)
- 7-Fluoro-1-methyl-1H-indole (CAS 1146637-25-3)
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- 7-Fluoro-4-methyl-1H-indole (CAS 1268052-65-8)
Recommended Standards
- 2-(3-Fluorophenyl)propanenitrile (CAS 1096868-17-5)
- N-Nitroso-N-methyl-3-aminopropionic Acid-d3, Methyl Ester (CAS 1246815-46-2)
- Fumaric Acid Monoethyl-d5 Ester (CAS 1266398-64-4)
- (3-Ethynyl-2-fluorophenyl)methanamine (CAS 1061650-53-0)
- 936940-12-4 1-(1,3,5-Trimethyl-1H-pyrazol-4-yl)ethan-1-amine DTXSID40598870 (CAS 936940-12-4)
- 4-({[2-(pyridin-4-yl)ethyl]amino}methyl)benzoic acid dihydrochloride (CAS 1384427-26-2)
- A23187 free acid (CAS 52665-69-7)
- 4-Bromo-2-(difluoromethyl)-5-iodo-3-methoxypyridine (CAS 1806070-25-6)
- 1-Hydroxypyrrolidine-2,5-dione compound with dicyclohexylamine (1:1) (CAS 82911-72-6)
- Methyl 4-(5-amino-1,3,4-thiadiazol-2-yl)benzoate (CAS 51542-42-8)
- N1-benzyl-2-methylpropane-1,3-diamine (CAS 1250405-19-6)
- Verapamil Impurity 20 (CAS 27339-25-9)
- 2-(2-(Methoxymethyl)-1H-benzo[d]imidazol-1-yl)acetamide (CAS 893631-60-2)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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