Verapamil Impurity 20 CAS 27339-25-9
| CAS No. | 27339-25-9 |
| Molecular Formula | C16H21NO3 |
| Molecular Weight | 275.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Verapamil Impurity 20 (CAS 27339-25-9, C16H21NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H21NO3, Verapamil Impurity 20 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 275.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Verapamil Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H21NO3 |
| Molecular Weight | 275.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 1 |
Related Verapamil Standards
- Verapamil Impurity 33 (CAS 27487-66-7)
- Verapamil Impurity N1 (CAS 102201-30-9)
- Verapamil EP Impurity D (CAS 36770-74-8)
- Verapamil Impurity 17 (CAS CATO-C4X-177817)
- Verapamil EP Impurity F (CAS 34245-14-2)
- Verapamil Impurity 19 (CAS CATO-C4X-177819)
- Verapamil Impurity 51 (CAS CATO-C4X-177851)
- Verapamil Impurity 52 (CAS CATO-C4X-177852)
Recommended Standards
- Propranolol Impurity 39 (CAS CATO-C4X-151939)
- Upadacitinib Impurity 71 (CAS 2411540-29-7)
- Atropine EP Impurity B (CAS 16839-98-8)
- Rolipram (CAS 61413-54-5)
- Loratadine Impurity 14 (CAS 38089-93-9)
- Lapatinib Impurity 43 (CAS CATO-C4X-119143)
- Dotinurad Impurity 214 (CAS CATO-C4X-2494214)
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- 2-(2-Methoxyethoxy)acetonitrile (CAS 135290-24-3)
- 4-(Aminomethyl)-1-methylpiperidin-4-ol dihydrochloride (CAS 23804-63-9)
- Tristearin-1,1,1-13C3 (CAS 287100-84-9)
- Methyl 2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxylate (CAS 1018975-69-3)
- HIV (gp120) Antigenic Peptide (H-2982.0500) (CAS 198636-94-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com