3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-chlorophenyl)thiophen-2-yl)boronate CAS 1162204-77-4
| CAS No. | 1162204-77-4 |
| Molecular Formula | C16H20BClO3S |
| Molecular Weight | 338.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-chlorophenyl)thiophen-2-yl)boronate.
CATO supplies 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-chlorophenyl)thiophen-2-yl)boronate (CAS 1162204-77-4), a certified reference material (molecular formula C16H20BClO3S, MW 338.66 g/mol) for analytical method development and quality control.
The molecular framework of 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-chlorophenyl)thiophen-2-yl)boronate (C16H20BClO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-chlorophenyl)thiophen-2-yl)boronate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H20BClO3S |
| Molecular Weight | 338.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Hydroxy Standards
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- 2-Hydroxy-7-(methylthio)quinoline-3-carbaldehyde (CAS 873300-63-1)
- 1-(((9H-fluoren-9-yl)methoxy)carbonyl)-3-((tert-butoxycarbonyl)amino)azetidine-3-carboxylic acid (CAS 2137824-18-9)
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- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
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