5-Chloro-2-fluoroiodobenzene CAS 116272-42-5
| CAS No. | 116272-42-5 |
| Molecular Formula | C6H3ClFI |
| Molecular Weight | 256.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-2-fluoroiodobenzene (CAS 116272-42-5) is a high-purity analytical reference standard with the molecular formula C6H3ClFI and a molecular weight of 256.44 g/mol.
Structurally, 5-Chloro-2-fluoroiodobenzene (C6H3ClFI) contains fluorine/chlorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 256.44 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2-fluoroiodobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3ClFI |
| Molecular Weight | 256.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/I-containing |
Related Chloro Standards
- 1-Chloro-3-fluoro-5-iodobenzene (CAS 1270019-81-2)
- 1-Chloro-3-fluoro-2-iodobenzene (CAS 127654-70-0)
- 1-Chloro-2-fluoro-6-iodobenzene (CAS 348642-49-9)
- 1-Chloro-4-fluoro-2-iodobenzene (CAS 202982-68-1)
- 4-Chloro-2-fluoroiodobenzene (CAS 6797-79-1)
- 4-Chloro-3-fluoroiodobenzene (CAS 202982-67-0)
- 2-Chloro-5-iodopyrimidin-4(3H)-one (CAS 1226881-10-2)
- 6-Chloro-5-iodopyrimidin-4-ol (CAS 1384431-15-5)
Recommended Standards
- N-Nitroso-N-methyl-N-tetradecylamine (CAS 75881-20-8)
- 1,2-Di(piperidin-1-yl)ethane-1,2-dithione (CAS 24528-76-5)
- 41203-22-9 1,4,8,11-Tetraazacyclotetradecane, 1,4,8,11-tetramethyl- 1,4,8,11-Tetramethyl-1,4,8,11-tetrazacyclotetradecane (CAS 41203-22-9)
- 83B68V00D8 22890-11-5 Capramidopropyl dimethylamine Decanamide, N-(3-(dimethylamino)propyl)- N-(3-(Dimethylamino)propyl)decan-1-amide EINECS 245-306-7 UNII-83B68V00D8 (CAS 22890-11-5)
- (4,6-Dimethoxypyrimidin-2-yl)methanamine (CAS 771582-35-5)
- 2-(Benzylamino)-N-cyclohexylbenzamide (CAS 1380589-73-0)
- 2-(4-Cyclopentylpiperazin-1-yl)-N-(prop-2-yn-1-yl)acetamide (CAS 1252133-68-8)
- VApreotide (acetate) (CAS 849479-74-9)
- 1-(6-Cyclopropylamino-pyrimidin-4-yl)-piperidine-3-carboxylic acid (CAS 1353989-80-6)
- cyclopropyl(4-methyl-1,3-thiazol-2-yl)methanamine (CAS 1211511-32-8)
- (2S,4S)-4-[4-(Acetylamino)phenoxy]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid (CAS 1354485-11-2)
- tert-butyl 3-methyl-1,4-diazepane-1-carboxylate (CAS 194032-35-4)
- 2-((Benzyloxy)carbonyl)cyclopropane-1-carboxylic acid (CAS 2166787-71-7)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com