6-Fluoroquinoline-3-carboxylic acid CAS 116293-90-4
| CAS No. | 116293-90-4 |
| Molecular Formula | C10H16FNO2 |
| Molecular Weight | 201.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Fluoroquinoline-3-carboxylic acid.
6-Fluoroquinoline-3-carboxylic acid (CAS 116293-90-4) is a high-purity analytical reference standard with the molecular formula C10H16FNO2 and a molecular weight of 201.24 g/mol.
The molecular framework of 6-Fluoroquinoline-3-carboxylic acid (C10H16FNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Fluoroquinoline-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H16FNO2 |
| Molecular Weight | 201.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoroquinoline Standards
- 6-fluoroquinoline-2-carboxylic acid (CAS 86324-51-8)
- 8-Fluoroquinoline-3-carbohydrazide (CAS 1307237-21-3)
- Methyl 6-fluoroquinoline-8-carboxylate (CAS 1368396-99-9)
- Methyl 5-fluoroquinoline-3-carboxylate (CAS 1415989-47-7)
- Methyl 7-fluoroquinoline-3-carboxylate (CAS 1415989-48-8)
- Methyl 5-fluoroquinoline-2-carboxylate (CAS 1420793-19-6)
- Methyl 7-fluoroquinoline-8-carboxylate (CAS 1541859-31-7)
- Methyl 6-fluoroquinoline-3-carboxylate (CAS 1573997-71-3)
Recommended Standards
- (3S)-6-fluoro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1161833-81-3)
- 3-(4-Fluorophenyl)-4-methylaniline (CAS 1175834-34-0)
- 2-(4-Fluoro-3,5-dimethylphenyl)pyridine (CAS 1151979-05-3)
- (6-Fluoro-[1,1'-biphenyl]-3-yl)methanamine (CAS 1181566-38-0)
- 8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbaldehyde (CAS 881841-42-5)
- 3-(4-Chlorophenyl)-4-(3-methoxybenzoyl)-1-phenylpyrrolidine (CAS 343374-91-4)
- 4-(Difluoromethyl)-3-hydroxy-5-(trifluoromethoxy)picolinaldehyde (CAS 1804836-83-6)
- 3-Isopropyl-[1,2,4]triazolo[4,3-b]pyridazine-6-carbaldehyde (CAS 1097874-56-0)
- 2-(2,6-Diethylphenyl)-1,3-dioxoisoindoline-5-carboxylic acid (CAS 100844-07-3)
- 2-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (CAS 847801-93-8)
- methyl 4-oxo-3-(2-phenylethyl)-2-sulfanyl-3,4-dihydroquinazoline-7-carboxylate (CAS 309750-70-7)
- 6-bromo-1,4-dioxaspiro[4.7]dodecane (CAS 73274-50-7)
- 3-(5-Amino-2-methyl-1H-benzo[d]imidazol-1-yl)propan-1-ol dihydrochloride (CAS 1185134-22-8)
- Cycloaspeptide D (CAS 691363-62-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com