(3Z)-1-(Pyrimidin-2-yl)-3-({[4-(trifluoromethoxy)phenyl]amino}methylidene)pyrrolidin-2-one CAS 1164518-09-5
| CAS No. | 1164518-09-5 |
| Molecular Formula | C16H13F3N4O2 |
| Molecular Weight | 350.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3Z)-1-(Pyrimidin-2-yl)-3-({[4-(trifluoromethoxy)phenyl]amino}methylidene)pyrrolidin-2-one.
(3Z)-1-(Pyrimidin-2-yl)-3-({[4-(trifluoromethoxy)phenyl]amino}methylidene)pyrrolidin-2-one (CAS 1164518-09-5) is a high-purity analytical reference standard with the molecular formula C16H13F3N4O2 and a molecular weight of 350.30 g/mol.
Based on its molecular formula C16H13F3N4O2, (3Z)-1-(Pyrimidin-2-yl)-3-({[4-(trifluoromethoxy)phenyl]amino}methylidene)pyrrolidin-2-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 350.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3Z)-1-(Pyrimidin-2-yl)-3-({[4-(trifluoromethoxy)phenyl]amino}methylidene)pyrrolidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13F3N4O2 |
| Molecular Weight | 350.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Z Standards
- Methyl 4-((2-(2-(pyrimidin-2-yl)-1H-imidazol-1-yl)ethyl)carbamoyl)benzoate (CAS 1448027-52-8)
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Recommended Standards
- Prodiamine (CAS 29091-21-2)
- tert-Butyl (2S,5S)-2,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate (CAS 1260588-12-2)
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- tert-Butyl (3S,5S)-3,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate (CAS 1260588-13-3)
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