tert-Butyl (3S,5S)-3,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate CAS 1260588-13-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1260588-13-3
Molecular FormulaC13H20F6N2O2
Molecular Weight350.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl (3S,5S)-3,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate CAS 1260588-13-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl (3S,5S)-3,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate.

tert-Butyl (3S,5S)-3,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate (CAS 1260588-13-3) is a high-purity analytical reference standard with the molecular formula C13H20F6N2O2 and a molecular weight of 350.30 g/mol.

tert-Butyl (3S,5S)-3,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate (C13H20F6N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl (3S,5S)-3,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H20F6N2O2
Molecular Weight350.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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