2-(2,4-Difluorophenyl)-6-[(2E)-3-(dimethylamino)prop-2-enoyl]-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione CAS 1164548-78-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1164548-78-0
Molecular FormulaC15H14F2N4O3
Molecular Weight336.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2,4-Difluorophenyl)-6-[(2E)-3-(dimethylamino)prop-2-enoyl]-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione CAS 1164548-78-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2,4-Difluorophenyl)-6-[(2E)-3-(dimethylamino)prop-2-enoyl]-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione.

2-(2,4-Difluorophenyl)-6-[(2E)-3-(dimethylamino)prop-2-enoyl]-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (CAS 1164548-78-0), molecular formula C15H14F2N4O3 and molecular weight 336.29 g/mol, is a CATO reference standard with documented purity and traceability.

2-(2,4-Difluorophenyl)-6-[(2E)-3-(dimethylamino)prop-2-enoyl]-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (C15H14F2N4O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(2,4-Difluorophenyl)-6-[(2E)-3-(dimethylamino)prop-2-enoyl]-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H14F2N4O3
Molecular Weight336.29 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms4

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