Idebenone Impurity 11 CAS 116460-81-2
| CAS No. | 116460-81-2 |
| Molecular Formula | C18H28O4 |
| Molecular Weight | 308.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 308.41 g/mol gives Idebenone Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Idebenone Impurity 11 (CAS 116460-81-2) is a certified pharmaceutical impurity reference standard with the molecular formula C18H28O4 and a molecular weight of 308.41 g/mol.
The molecular framework of Idebenone Impurity 11 (C18H28O4) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H28O4 |
| Molecular Weight | 308.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ＞98% |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
Related Idebenone Standards
Recommended Standards
- Levonorgestrel Impurity 33 (CAS 93798-38-0)
- Levonorgestrel EP Impurity W (CAS 155683-59-3)
- Gestrinone (CAS 16320-04-0)
- Exemestane EP Impurity C (CAS 2130745-60-5)
- Cimetidine EP Impurity C Dihydrochloride (CAS 52568-80-6)
- Imipenem Impurity 7 (CAS 130792-44-8)
- Azilsartan impurity 146 (CAS CATO-C4X-1096146)
- 5-Bromo-2-methyl-n-(pyridin-2-ylmethyl)thiophene-3-sulfonamide (CAS 1427541-23-8)
- (2-(3-Fluorophenyl)thiazol-4-yl)methanamine (CAS 885280-31-9)
- 2,7-Dichloro-8-methylquinoline-3-carbonitrile (CAS 948291-65-4)
- 6-(4-(Methylsulfonyl)phenyl)nicotinaldehyde (CAS 834884-68-3)
- 3-(5-Iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid (CAS 22483-98-3)
- Methyl 4-chloro-6-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 1804890-92-3)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
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