7-Chloro-4-(trifluoromethyl)-1H-indole CAS 1167055-96-0
| CAS No. | 1167055-96-0 |
| Molecular Formula | C9H5ClF3N |
| Molecular Weight | 219.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Chloro-4-(trifluoromethyl)-1H-indole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 7-Chloro-4-(trifluoromethyl)-1H-indole (CAS 1167055-96-0), a certified reference material (molecular formula C9H5ClF3N, MW 219.59 g/mol) for analytical method development and quality control.
Structurally, 7-Chloro-4-(trifluoromethyl)-1H-indole (C9H5ClF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 219.59 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-4-(trifluoromethyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5ClF3N |
| Molecular Weight | 219.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(3-Chloro-4-(trifluoromethyl)phenyl)acetonitrile (CAS 1000530-58-4)
- 2-(4-Chloro-3-nitro-1H-pyrazol-1-yl)acetohydrazide (CAS 1004644-14-7)
- 5-Chloro-2-(trifluoromethyl)-1H-indole (CAS 1007235-35-9)
- 2-Chloro-n-(2-hydroxyethyl)-n-(2,2,2-trifluoroethyl)acetamide (CAS 1183001-67-3)
- 5-Chloro-6-(trifluoromethyl)-1H-indole (CAS 1186404-60-3)
- 2-Chloro-2-[3-(trifluoromethyl)phenyl]acetonitrile (CAS 1247690-29-4)
- 2-Chloro-2-(4-(trifluoromethyl)phenyl)acetonitrile (CAS 1248366-32-6)
- 7-chloro-2-(trifluoromethyl)-1H-indole (CAS 1369551-50-7)
Recommended Standards
- 4-Chloro-2,6-dimethoxy-5-nitropyrimidine (CAS 60331-03-5)
- 2-Chloro-4,6-dimethoxy-5-nitropyrimidine (CAS 478010-54-7)
- 1H-Pyrazole-3-carboxylic acid, 4-nitro-, 2-chloroethyl ester (CAS 923283-70-9)
- 2-(2-Chloro-3-(trifluoromethyl)phenyl)acetonitrile (CAS 22902-81-4)
- 3-Fluoro-5-formyl-4-hydroxybenzoic acid (CAS 2166833-12-9)
- 6-(p-Tolyl)nicotinaldehyde (CAS 898795-75-0)
- 2-(3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propyl)isoindoline-1,3-dione (CAS 1628595-38-9)
- 7-(methoxymethyl)-1,3,5-trimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine (CAS 2627592-44-1)
- 4-(4-aminophenyl)-1-methyl-1{H}-pyrazolo[3,4-{b}]pyridine-3-carboxylic acid (CAS 1354704-66-7)
- 2-(4-chloro-3-methylphenoxy)acetamide (CAS 7399-59-9)
- Tert-butyl (4-(7-fluoro-1-oxoisoindolin-2-yl)cyclohexyl)carbamate (CAS 1713160-81-6)
- 6-Bromo-2-(4-ethoxyphenyl)quinoline-4-carboxylic acid (CAS 351001-28-0)
- 3-(Piperazin-1-yl)propan-1-amine (CAS 34885-02-4)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
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