6-Bromo-2-(4-ethoxyphenyl)quinoline-4-carboxylic acid CAS 351001-28-0
| CAS No. | 351001-28-0 |
| Molecular Formula | C18H14BrNO3 |
| Molecular Weight | 372.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 372.21 g/mol gives 6-Bromo-2-(4-ethoxyphenyl)quinoline-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Bromo-2-(4-ethoxyphenyl)quinoline-4-carboxylic acid (CAS 351001-28-0) is a high-purity analytical reference standard with the molecular formula C18H14BrNO3 and a molecular weight of 372.21 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 6-Bromo-2-(4-ethoxyphenyl)quinoline-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 372.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Bromo-2-(4-ethoxyphenyl)quinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14BrNO3 |
| Molecular Weight | 372.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- Ethyl 9-bromo-8-fluoro-4,5-dihydrobenzo[2,3]oxepino[4,5-d]thiazole-2-carboxylate (CAS 1451085-03-2)
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- N'-((5-Bromo-2-fluoropyridin-3-yl)methylene)-4-methylbenzenesulfonohydrazide (CAS 2586232-99-5)
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Recommended Standards
- Ethyl 3-((1-(4-bromophenyl)-3-methoxy-3-oxopropyl)amino)-3-oxopropanoate (CAS 383147-00-0)
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- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(3-(trifluoromethyl)phenyl)thiophen-2-yl)boronate (CAS 2223011-20-7)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(2-(trifluoromethyl)phenyl)thiophen-2-yl)boronate (CAS 2223042-41-7)
- 2,3-Dimethoxy-6-methylanthracene-9,10-dione (CAS 105706-01-2)
- 2-((4,6-Dimercapto-1,3,5-triazin-2-yl)(phenyl)amino)acetic acid (CAS 175161-86-1)
- 2-(2-Methoxy-4-methylphenoxy)ethane-1-sulfonyl chloride (CAS 1339846-04-6)
- 4-(4-Fluorophenoxy)-6-(methylthio)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 341968-31-8)
- 1-(3-Bromophenyl)-3-(dimethylamino)prop-2-en-1-one (CAS 163852-04-8)
- 4-(2-Fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]tetrahydro-1(2H)-pyrazinecarbothioamide (CAS 497060-20-5)
- 4-(2-Methyl-1H-indol-3-yl)-1,3-thiazol-2-amine (CAS 50825-19-9)
- 5,6-dimethoxy-1,2-dihydroquinazolin-2-one (CAS 92210-41-8)
- 2-Amino-6-(hydroxymethyl)-4-(4-hydroxyphenyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile (CAS 899366-91-7)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
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