Apremilast Impurity 33 HCl CAS 1167056-61-2
| CAS No. | 1167056-61-2 |
| Molecular Formula | C9H9NO4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Apremilast Impurity 33 HCl.
Apremilast Impurity 33 HCl (CAS 1167056-61-2) is a high-purity analytical reference standard with the molecular formula C9H9NO4HCl and a molecular weight of 231.63 g/mol.
Apremilast Impurity 33 HCl (C9H9NO4HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Apremilast Impurity 33 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H9NO4 HCl |
| Molecular Weight | 231.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Apremilast Standards
- Apremilast impurity 97 (CAS 1000342-08-4)
- Apremilast Impurity 86 (CAS 106860-70-2)
- Apremilast Impurity 108 (CAS 120-25-2)
- Apremilast Impurity 57 (CAS 1255909-25-1)
- Apremilast-d8 (CAS 1258597-45-3)
- Apremilast-d5 (CAS 1258597-47-5)
- Apremilast Impurity 56 (CAS 1284768-38-2)
- Apremilast impurity 18 (CAS 1384439-79-5)
Recommended Standards
- 5,10-Dihydroindolo[3,2-b]indole (CAS 3682-85-7)
- Bis(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)methane (CAS 5228-95-5)
- 4-(1-(p-Tolyl)-1H-pyrazol-5-yl)pyridine (CAS 1269291-28-2)
- 6-Fluoropyrazin-2-amine (CAS 1246466-74-9)
- Methyl 2-(thiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 301319-85-7)
- 2,2,2-Trifluoro-N-(5-methoxy-2-methylphenyl)acetamide (CAS 68545-88-0)
- 20-Hydroxy-3-oxo-28-lupanoic acid 93372-87-3 C30H48O4 W2492 (CAS 93372-87-3)
- N-(4-chloro-3-nitrophenyl)-4-methylpiperazine-1-carboxamide (CAS 1858255-73-8)
- Ethyl (4-(4-carboxyphenyl)-1,2,3-triazol-1-yl)acetate 1779136-81-0 (CAS 1779136-81-0)
- C-Peptide 2 (rat) (CAS 41594-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com