Apremilast Impurity 108 CAS 120-25-2
| CAS No. | 120-25-2 |
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Apremilast Impurity 108 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 180.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Apremilast Impurity 108 (CAS 120-25-2, C10H12O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Apremilast Impurity 108 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Apremilast Standards
- Apremilast Impurity 67 (CAS 5434-20-8)
- Apremilast Impurity 110 (CAS 34184-93-5)
- Apremilast Impurity 66 (CAS 587-48-4)
- Apremilast Impurity 57 (CAS 3096-76-2)
- Apremilast Impurity 80 (CAS 60758-86-3)
- Apremilast Impurity 18 (CAS 51673-94-0)
- Apremilast Impurity 109 (CAS 2029-94-9)
- Apremilast Impurity 86 (CAS 106860-70-2)
Recommended Standards
- 2-(3,4-Dimethoxyphenyl)acetaldehyde (CAS 5703-21-9)
- Vardenafil Impurity 20 (CAS 879-57-2)
- 4-Hydroxy-4-phenylbutanoic acid (CAS 34674-93-6)
- (2R,3S)-3-amino-2-hydroxy-3-phenylpropanamide (CAS CATO-C4X-111546)
- Trelagliptin Impurity 46 (CAS 1261742-22-6)
- Lusutrombopag Impurity 28 (CAS CATO-C4X-208428)
- Etoricoxib Impurity 18 (CAS 1027162-35-1)
- 5-Amino-3-(4-tetrahydropyranyl)pyrazole (CAS 1000896-69-4)
- Pemetrexed Impurity 53 (CAS 1320346-37-9)
- Methyl 2-amino-5-[3-(trifluoromethyl)phenyl]benzoate (CAS 926236-39-7)
- tert-Butyl 3-(2-mercaptoethyl)piperidine-1-carboxylate (CAS 1420866-00-7)
- 3-((3-Amino-3-oxopropyl)amino)propanoic acid (CAS 5493-40-3)
- Bis(1-(isobutyryloxy)-2,2,4-trimethylpentan-3-yl) adipate (CAS 100208-33-1)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com