6-Hydroxy-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile CAS 1167056-72-5
| CAS No. | 1167056-72-5 |
| Molecular Formula | C8H5N3O |
| Molecular Weight | 159.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Hydroxy-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Hydroxy-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1167056-72-5) is a high-purity analytical reference standard with the molecular formula C8H5N3O and a molecular weight of 159.14 g/mol.
The molecular framework of 6-Hydroxy-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (C8H5N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5N3O |
| Molecular Weight | 159.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 3 |
Related Hydroxy Standards
- 3-Hydroxy-4-cyano (1H)Indazole (CAS 1000342-91-5)
- 5-Hydroxy-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS 1016241-62-5)
- 5-Hydroxy-3-methyl-2-oxoimidazolidine-1-carboxamide (CAS 162830-39-9)
- Methyl 3-hydroxy-2-nitrosopent-2-enoate (CAS 1937358-65-0)
- (R)-2-Hydroxy-1-methyl-5-oxopyrrolidine-2-carboxylic acid (CAS 22671-35-8)
- (S)-2-(4-Hydroxy-2-oxopyrrolidin-1-yl)aceticacid (CAS 99437-11-3)
- 1-Hydroxy-1H-benzo[d]imidazole-2-carbonitrile (CAS 40159-90-8)
- 2-Hydroxy-1h-pyrrolo[3,2-b]pyridine-3-carbonitrile (CAS 32501-04-5)
Recommended Standards
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile (CAS 1167056-59-8)
- Isobenzofuro[4,5-d]oxazole (CAS 117272-33-0)
- Benzofuro[5,4-d]oxazole (CAS 115422-75-8)
- trans-ACBD (CAS 117488-23-0)
- Ethyl 2-(4-(3-(trifluoromethyl)benzoyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-3-yl)acetate (CAS 439112-05-7)
- (-)-Ilaprazole (CAS 834897-64-2)
- N-(3-methoxybenzyl)propan-1-amine hydrochloride (CAS 1048948-07-7)
- N-(azetidin-3-yl)-N-methylacetamide hydrochloride (CAS 935668-15-8)
- 7-chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1547041-34-8)
- 2,4-Di-tert-butyl-6-nitrophenol (CAS 20039-94-5)
- (4-Nitrophenyl)[5-(trifluoromethyl)-2,3-dihydro-1H-1,4-diazepin-1-yl]methanone (CAS 478249-14-8)
- 4-Bromo-6-fluoroquinolin-2(1H)-one (CAS 2097816-14-1)
- N-(3,4-Dimethoxybenzyl)-1-oxa-4-thia-8-azaspiro[4.5]decane-8-carboxamide (CAS 1351615-93-4)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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