(R)-2-Hydroxy-1-methyl-5-oxopyrrolidine-2-carboxylic acid CAS 22671-35-8
| CAS No. | 22671-35-8 |
| Molecular Formula | C6H9NO4 |
| Molecular Weight | 159.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(R)-2-Hydroxy-1-methyl-5-oxopyrrolidine-2-carboxylic acid (CAS 22671-35-8), molecular formula C6H9NO4 and molecular weight 159.14 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H9NO4, (R)-2-Hydroxy-1-methyl-5-oxopyrrolidine-2-carboxylic acid contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 159.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9NO4 |
| Molecular Weight | 159.14 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related R Standards
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Recommended Standards
- (R)-2-Amino-2-((R)-5-oxotetrahydrofuran-2-yl)acetic acid (CAS 714194-19-1)
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- (4S,5R)-3,5-Dimethyl-2-oxooxazolidine-4-carboxylic acid (CAS 204386-94-7)
- (R)-3-Acetyloxazolidine-4-carboxylic acid (CAS 344738-31-4)
- 2-(Nitromethylene)imidazolidine (CAS 13623-98-8)
- 2-[3-(Difluoromethyl)-1H-pyrazol-1-yl]propanoic acid (CAS 1823791-94-1)
- 7-Isopropyl-4-methyl-1H-indene (CAS 144284-62-8)
- 4-[(2-Fluorobenzyl)oxy]-3-methoxybenzoyl chloride (CAS 926028-23-1)
- 2-((4-Fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinoline (CAS 313981-60-1)
- 5-Chloro-2-methyl-4-((1-methylpiperidin-3-yl)amino)pyridazin-3(2H)-one (CAS 2060042-44-4)
- quinolin-8-ylmethanethiol (CAS 103264-35-3)
- 4-(2-Bromophenethyl)morpholine (CAS 736991-23-4)
- Indolizine-8-carboxylic acid (CAS 1526647-48-2)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
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