1-(Chloromethyl)-2-(trifluoromethoxy)benzene CAS 116827-40-8
| CAS No. | 116827-40-8 |
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H6ClF3O, 1-(Chloromethyl)-2-(trifluoromethoxy)benzene contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 210.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(Chloromethyl)-2-(trifluoromethoxy)benzene (CAS 116827-40-8) is a high-purity analytical reference standard with the molecular formula C8H6ClF3O and a molecular weight of 210.58 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(Chloromethyl)-2-(trifluoromethoxy)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)-5-(trifluoromethyl)pyridin-3-amine (CAS 1227502-61-5)
- 2-Chloromethyl-3-trifluoromethyl-phenol (CAS 1261584-87-5)
- 5-(Chloromethyl)-4-methyl-2-(trifluoromethyl)pyrimidine (CAS 1638221-46-1)
- 4-(Chloromethyl)-5-(difluoromethyl)-3-fluoropyridin-2-amine (CAS 1804488-63-8)
- 5-(Chloromethyl)-3-(difluoromethyl)-4-fluoropyridin-2-amine (CAS 1804488-67-2)
- 4-(Chloromethyl)-6-(difluoromethyl)-3-fluoropyridin-2-amine (CAS 1804951-45-8)
- 5-(Chloromethyl)-6-(difluoromethyl)-3-fluoropyridin-2-amine (CAS 1804951-50-5)
- 4-(Chloromethyl)-3-(difluoromethyl)-6-fluoropyridin-2-amine (CAS 1805063-01-7)
Recommended Standards
- 1-Chloro-3-(2,2,2-trifluoroethoxy)benzene (CAS 106854-78-8)
- (4-Chloro-6-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1196154-09-2)
- 1-(2-Chloropyridin-4-yl)-2,2,2-trifluoroethan-1-amine (CAS 1060811-95-1)
- S 2-Chloro-1-(2,3,4-trifluoro-phenyl)-ethanol 1204756-51-3 A1-02931 (CAS 1204756-51-3)
- Formanilide (CAS 103-70-8)
- 2-[1-(4-Chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine oxide (CAS 110203-91-3)
- Euphorbol (CAS 566-14-3)
- 4-Amino-2-chloro-3-methoxypyridine (CAS 1227600-23-8)
- (R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one (CAS 103343-65-3)
- 1-(Tert-butyl) 3-ethyl (3S,4R)-4-hydroxypyrrolidine-1,3-dicarboxylate (CAS 849935-85-9)
- 2-Hydroxyoctadecanoic Acid (CAS 629-22-1)
- tert-Butyl 3-methoxypropanoate (CAS 112032-54-9)
- N,N-dimethyl-2-((4-methyl-1,2,3-thiadiazol-5-yl)thio)ethan-1-amine (CAS 338420-57-8)
- Protein Kinase C? Peptide Substrate (CAS 120253-69-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com