2-Chloromethyl-3-trifluoromethyl-phenol CAS 1261584-87-5
| CAS No. | 1261584-87-5 |
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 210.58 g/mol gives 2-Chloromethyl-3-trifluoromethyl-phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloromethyl-3-trifluoromethyl-phenol (CAS 1261584-87-5) is a high-purity analytical reference standard with the molecular formula C8H6ClF3O and a molecular weight of 210.58 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloromethyl-3-trifluoromethyl-phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 210.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloromethyl Standards
- 1-(Chloromethyl)-2-(trifluoromethoxy)benzene (CAS 116827-40-8)
- 2-(Chloromethyl)-5-(trifluoromethyl)pyridin-3-amine (CAS 1227502-61-5)
- 5-(Chloromethyl)-4-methyl-2-(trifluoromethyl)pyrimidine (CAS 1638221-46-1)
- 4-(Chloromethyl)-5-(difluoromethyl)-3-fluoropyridin-2-amine (CAS 1804488-63-8)
- 5-(Chloromethyl)-3-(difluoromethyl)-4-fluoropyridin-2-amine (CAS 1804488-67-2)
- 4-(Chloromethyl)-6-(difluoromethyl)-3-fluoropyridin-2-amine (CAS 1804951-45-8)
- 5-(Chloromethyl)-6-(difluoromethyl)-3-fluoropyridin-2-amine (CAS 1804951-50-5)
- 4-(Chloromethyl)-3-(difluoromethyl)-6-fluoropyridin-2-amine (CAS 1805063-01-7)
Recommended Standards
- (6-Chloro-3-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1256786-33-0)
- 1-(3-Chloropyridin-2-yl)-2,2,2-trifluoroethan-1-amine (CAS 1270393-54-8)
- (2-Chloro-5-(trifluoromethyl)pyridin-3-yl)methanamine (CAS 1245916-03-3)
- 3-Chloro-4,5-diaminobenzotrifluoride (CAS 132915-80-1)
- 1,4-Dichloro-2-iodo-6-nitrobenzene (CAS 860688-24-0)
- Methyl trans-3-{[(tert-butoxy)carbonyl]amino}-1-methylcyclobutane-1-carboxylate (CAS 1946010-92-9)
- 2-(2,2-Diphenylacetyl)-3-(propylidenehydrazineylidene)-2,3-dihydro-1H-inden-1-one (CAS 1119449-20-5)
- 2-Chloro-4-methyl-6-(trifluoromethyl)nicotinic acid (CAS 280567-96-6)
- 2-(Aminomethyl)-5-chloro-6-(difluoromethyl)-3-fluoropyridine (CAS 1805364-32-2)
- tert-Butyl ((1H-pyrrolo[2,3-c]pyridin-5-yl)methyl)carbamate (CAS 267875-33-2)
- (2S,4R)-Methyl 4-hydroxy-5-oxotetrahydrofuran-2-carboxylate (CAS 123356-13-8)
- 4-Azetidinomethyl-3-fluorobenzophenone (CAS 898756-52-0)
- N'-(6-chloropyridin-2-yl)cyclopropanecarbohydrazide (CAS 478064-08-3)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
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