Olmesartan Impurity 34 CAS 116857-04-6

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.116857-04-6
Molecular FormulaC5H6Cl2O3
Molecular Weight185.01 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Olmesartan Impurity 34 CAS 116857-04-6 chemical structure

Description

CATO supplies Olmesartan Impurity 34 (CAS 116857-04-6), a pharmacopoeial impurity reference standard (molecular formula C5H6Cl2O3, MW 185.01 g/mol) used for the identification and quantification of trace impurities in APIs.

Olmesartan Impurity 34 (C5H6Cl2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC5H6Cl2O3
Molecular Weight185.01 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityHygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1990
Halogen ContentCl-containing

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