4-Bromo-2-((tert-butyldimethylsilyl)oxy)-6-methylpyridine CAS 1169472-52-9
| CAS No. | 1169472-52-9 |
| Molecular Formula | C12H20BrNOSi |
| Molecular Weight | 302.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-2-((tert-butyldimethylsilyl)oxy)-6-methylpyridine (CAS 1169472-52-9), molecular formula C12H20BrNOSi and molecular weight 302.28 g/mol, is a CATO reference standard with documented purity and traceability.
4-Bromo-2-((tert-butyldimethylsilyl)oxy)-6-methylpyridine (C12H20BrNOSi) contains an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-2-((tert-butyldimethylsilyl)oxy)-6-methylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H20BrNOSi |
| Molecular Weight | 302.28 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-6-(((tert-butyldimethylsilyl)oxy)methyl)pyridine (CAS 150058-63-2)
- 3-bromo-5-(((tert-butyldimethylsilyl)oxy)methyl)pyridine (CAS 152351-91-2)
- 2-Bromo-3-(((tert-butyldimethylsilyl)oxy)methyl)pyridine (CAS 524019-50-9)
- 2-Bromo-4-(((tert-butyldimethylsilyl)oxy)methyl)pyridine (CAS 815584-38-4)
- 5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)pyridine (CAS 88139-92-8)
- 4-Bromo-6-t-butyl-2-mercaptobenzothiazole (CAS 1199773-20-0)
- 2-bromo-7-methoxy-3-methyl-9H-carbazole (CAS 2649492-68-0)
- 2-Bromo-N,N-dicyclohexylacetamide (CAS 54700-62-8)
Recommended Standards
- 1-(3-(3,6-Dihydroxy-2-methylbenzoyl)-2,4-dihydroxyphenyl)ethan-1-one (CAS 115834-34-9)
- 2,5-Difluoro-4-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)aniline (CAS 1225278-35-2)
- 2,5,7-Trihydroxy-8-methoxyflavanone (CAS 112408-71-6)
- 4-((3,5-Difluorophenyl)amino)-6-(pyrrolidin-1-yl)-1,3,5-triazine-2-carbonitrile (CAS 1311279-71-6)
- V-A-I-T-V-L-V-K (CAS 145224-99-3)
- 5,7-dichloro-6-methylquinoline (CAS 1909305-11-8)
- methyl 2,3-dimethyl-2H-indazole-5-carboxylate (CAS 2114095-94-0)
- (S)-2-Amino-3-(2,4,5-trifluorophenyl)propanoic acid (CAS 749847-57-2)
- tert-butyl N-[(1R,2R)-2-methanesulfonamidocyclohexyl]carbamate (CAS 1807938-41-5)
- 8-Chloro-2-(4-hydroxyphenyl)-4H-chromen-4-one (CAS 2413193-29-8)
- trans-2-Ethoxy-5-(1-propenyl)phenol (CAS 63477-41-8)
- (6-IOdo-pyridin-3-yl)-dimethyl-amine (CAS 1935039-87-4)
- 1-(4-Fluorophenyl)-5-methyl-1H-pyrazol-4-amine (CAS 1250791-76-4)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
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