1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbonitrile CAS 1171918-97-0
| CAS No. | 1171918-97-0 |
| Molecular Formula | C12H11ClF3N3 |
| Molecular Weight | 289.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbonitrile (C12H11ClF3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbonitrile (CAS 1171918-97-0), molecular formula C12H11ClF3N3 and molecular weight 289.68 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11ClF3N3 |
| Molecular Weight | 289.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
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- 3-(2,5-Dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]Dec-3-en-4-yl ethyl carbonate (CAS 382608-10-8)
- Levonorgestrel Impurity 33 (CAS 93798-38-0)
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- 6-(2-Chlorophenyl)-2-(2-morpholinoethyl)-4-phenylpyridazin-3(2H)-one (CAS 23348-35-8)
- 3-(3-aminophenyl)-5-(methoxymethyl)imidazolidine-2,4-dione (CAS 1531545-30-8)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
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