4-Chloro-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine hydrochloride CAS 1172808-59-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1172808-59-1
Molecular FormulaC7H8ClN3
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine hydrochloride CAS 1172808-59-1 chemical structure

Description

The occurrence of 4-Chloro-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine hydrochloride is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Chloro-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine hydrochloride (CAS 1172808-59-1) is a high-purity analytical reference standard with the molecular formula C7H8ClN3HCl and a molecular weight of 206.07 g/mol.

The molecular framework of 4-Chloro-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine hydrochloride (C7H8ClN3HCl) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Chloro-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H8ClN3 HCl
Molecular Weight206.07 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms3

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