Gefitinib-d3 CAS 1173976-40-3
| CAS No. | 1173976-40-3 |
| Molecular Formula | - |
| Molecular Weight | 449.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 449.92 g/mol gives Gefitinib-d3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Gefitinib-d3 (CAS 1173976-40-3), a certified reference material (molecular formula C22H21D3ClFN4O3, MW 449.92 g/mol) for analytical method development and quality control.
Owing to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Gefitinib-d3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 449.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21D3ClFN4O3 |
| Molecular Weight | 449.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Gefitinib Standards
- Gefitinib Impurity 39 (CAS CATO-C4X-111739)
- Gefitinib Impurity 15 (CAS 1608115-59-8)
- Gefitinib (CAS 184475-35-2)
- Gefitinib Impurity 10 (CAS 1603814-04-5)
- Gefitinib Impurity 33 (CAS 909863-33-8)
- Gefitinib Impurity 34 (CAS CATO-C4X-111734)
- Gefitinib Impurity 37 (CAS CATO-C4X-111737)
- Gefitinib Impurity 43 (CAS CATO-C4X-111743)
Recommended Standards
- 1-{2-[7-(4-chloro-3-nitrophenyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-2,5-dimethyl-1H-pyrrole (CAS 439120-62-4)
- 1,1',1''-(1,3,5-Triazinane-1,3,5-triyl)tris(2-bromoethan-1-one) (CAS 92531-02-7)
- tert-Butyl 1-(2-((4-chlorophenyl)amino)-2-oxoethyl)-1H-benzo[e][1,3,4]thiadiazine-3-carboxylate 4,4-dioxide (CAS 1707587-05-0)
- ADAMTS-5 Inhibitor (CAS 929634-33-3)
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- 8-(1-Methoxyethyl)-2-methylimidazo[1,2-b]pyridazine-7-carboxylic acid (CAS 2434602-72-7)
- 4-(3-(3-Fluorophenyl)-3-oxopropyl)benzothialdehyde (CAS 898781-15-2)
- 3-Bromo-3'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1443305-31-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com