Cilastatin EP Impurity E CAS 1174657-07-8
| CAS No. | 1174657-07-8 |
| Molecular Formula | C10H17NO5S |
| Molecular Weight | 263.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Cilastatin EP Impurity E (CAS 1174657-07-8), a pharmacopoeial impurity reference standard (molecular formula C10H17NO5S, MW 263.31 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Cilastatin EP Impurity E (C10H17NO5S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 263.31 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17NO5S |
| Molecular Weight | 263.31 g/mol |
| Purity | >85% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Cilastatin Standards
- Cilastatin Impurity 28 (CAS CATO-C4X-196028)
- Cilastatin Impurity 15 (CAS 1114-50-7)
- Cilastatin Impurity 19 (CAS CATO-C4X-196019)
- Cilastatin Impurity 9 (CAS 131833-97-1)
- Cilastatin Impurity 29 (CAS 1022895-93-7)
- Cilastatin Impurity 47 (CAS 877758-94-6)
- Cilastatin EP Impurity H (CAS CATO-C4X-19605)
- Cilastatin Impurity 11 (CAS 78834-75-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com