1-(4-(Trifluoromethyl)benzyl)-1h-pyrazole-4-carboxylic acid CAS 1174666-17-1
| CAS No. | 1174666-17-1 |
| Molecular Formula | C12H9F3N2O2 |
| Molecular Weight | 270.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 270.21 g/mol gives 1-(4-(Trifluoromethyl)benzyl)-1h-pyrazole-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(4-(Trifluoromethyl)benzyl)-1h-pyrazole-4-carboxylic acid (CAS 1174666-17-1), a certified reference material (molecular formula C12H9F3N2O2, MW 270.21 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H9F3N2O2, 1-(4-(Trifluoromethyl)benzyl)-1h-pyrazole-4-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 270.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(4-(Trifluoromethyl)benzyl)-1h-pyrazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2O2 |
| Molecular Weight | 270.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 3-{[3-(trifluoromethyl)-1h-pyrazol-1-yl]methyl}benzoic acid (CAS 1004643-62-2)
- 4-{[3-(trifluoromethyl)-1h-pyrazol-1-yl]methyl}benzoic acid (CAS 1006482-42-3)
- 1-Benzyl-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 1152504-29-4)
- 5-Methyl-2-[3-(trifluoromethyl)phenyl]-1H-imidazole-4-carboxylic Acid (CAS 1153734-86-1)
- 5-Methyl-1-(2-(trifluoromethyl)phenyl)-1h-pyrazole-4-carboxylic acid (CAS 1169957-94-1)
- 1-(2-(Trifluoromethyl)benzyl)-1h-pyrazole-4-carboxylic acid (CAS 1177346-90-5)
- (3-((4-(Trifluoromethyl)pyrimidin-2-yl)oxy)phenyl)methanol (CAS 1215524-83-6)
- (4-((2-(Trifluoromethyl)pyrimidin-4-yl)oxy)phenyl)methanol (CAS 1215662-44-4)
Recommended Standards
- 3-methoxy-4-(4-(trifluoromethyl)-1H-imidazol-1-yl)benzaldehyde (CAS 1170734-96-9)
- 5-AMino-n-[4-(trifluoromethyl)phenyl]-1h-pyrazole-4-carboxamide (CAS 1186833-12-4)
- 4-Amino-7-(trifluoromethyl)quinoline-3-carbohydrazide (CAS 1208701-12-5)
- 2,2,2-Trifluoroethyl n-(isoquinolin-5-yl)carbamate (CAS 1152953-99-5)
- 4-(Aminomethyl)-1,2,3,4-tetrahydroquinolin-2-one (CAS 933698-79-4)
- Leucomyosuppressin (CAS 106884-19-9)
- Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-Leu-Arg-Pro-Gly-NH2 (CAS CATO-C4X-186231)
- [(3-Fluorophenyl)methyl](2-methylpropyl)amine (CAS 1019578-68-7)
- 2-Amino-N-(2-chloro-6-methylphenyl)acetamide hydrochloride (CAS 50416-18-7)
- Bortezomib Impurity 12 Trifluoroacetic Acid (CAS 477254-69-6)
- Diethyl 1-benzyl-1H-imidazole-4,5-dicarboxylate (CAS 1232-51-5)
- (2-(Benzo[d][1,3]dioxol-5-yldimethylsilyl)phenyl)methanol (CAS 1244855-75-1)
- (4-hydroxy-3-methoxyphenyl)(morpholino)methanethione (CAS 17692-71-6)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
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