(4-Chlorophenyl)(4-methylthiazol-2-yl)methanone CAS 1177235-48-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1177235-48-1
Molecular FormulaC11H8ClNOS
Molecular Weight237.71 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(4-Chlorophenyl)(4-methylthiazol-2-yl)methanone CAS 1177235-48-1 chemical structure

Description

(4-Chlorophenyl)(4-methylthiazol-2-yl)methanone (CAS 1177235-48-1) is a high-purity analytical reference standard with the molecular formula C11H8ClNOS and a molecular weight of 237.71 g/mol.

The molecular framework of (4-Chlorophenyl)(4-methylthiazol-2-yl)methanone (C11H8ClNOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (4-Chlorophenyl)(4-methylthiazol-2-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H8ClNOS
Molecular Weight237.71 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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