4-(3-Methoxyphenyl)-2-(piperazin-1-ylmethyl)thiazole dihydrochloride CAS 1177320-64-7
| CAS No. | 1177320-64-7 |
| Molecular Formula | C15H19N3OS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(3-Methoxyphenyl)-2-(piperazin-1-ylmethyl)thiazole dihydrochloride.
4-(3-Methoxyphenyl)-2-(piperazin-1-ylmethyl)thiazole dihydrochloride (CAS 1177320-64-7) is a high-purity analytical reference standard with the molecular formula C15H19N3OSHCl and a molecular weight of 325.86 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, 4-(3-Methoxyphenyl)-2-(piperazin-1-ylmethyl)thiazole dihydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(3-Methoxyphenyl)-2-(piperazin-1-ylmethyl)thiazole dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H19N3OS 2*HCl |
| Molecular Weight | 325.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methoxyphenyl Standards
- 3-(3-Methoxyphenyl)isonicotinic acid (CAS 100004-80-6)
- 3-(2-Methoxyphenyl)isonicotinic acid (CAS 100004-81-7)
- 2-(3-Methoxyphenyl)isonicotinic acid (CAS 100004-95-3)
- 2-(3-Methoxyphenyl)benzo[d]thiazole (CAS 10002-44-5)
- 4-(5-(4-Methoxyphenyl)oxazol-2-yl)aniline (CAS 10004-75-8)
- 2-(4-Methoxyphenyl)-6-(methylthio)-4H-thiopyran-4-one (CAS 1000574-20-8)
- Ethyl 2-{[2-(4-methoxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}acetate (CAS 100064-06-0)
- Methyl 5-(2-methoxyphenyl)-1H-pyrrole-2-carboxylate (CAS 1000682-34-7)
Recommended Standards
- 2-(2-Methyl-3-nitrophenyl)-N,N-dipropylacetamide (CAS 91374-22-0)
- 1-Ethyl-2-(thiophen-2-yl)-1H-indole-3-carbaldehyde (CAS 1244855-38-6)
- 4-(Difluoromethyl)-3,6-dihydroxypicolinoyl chloride (CAS 1806894-20-1)
- 3-(Cyclopropylmethoxy)piperidine (CAS 946725-59-3)
- 4-(5-Methylthiophen-2-yl)but-3-en-2-one (CAS 57558-97-1)
- 10-Methyl-2-nitroacridin-9(10H)-one (CAS 58658-02-9)
- Methyl 4-(2-acetylphenyl)-2-chlorobenzoate (CAS 1820711-85-0)
- Avatrombopag Impurity 60 (CAS CATO-C4X-223460)
- 1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]Heptan-1-yl)-N-(4-isopropylphenyl)methanesulfonamide (CAS 627844-63-7)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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