Avatrombopag Impurity 60 CAS CATO-C4X-223460
| CAS No. | CATO-C4X-223460 |
| Molecular Formula | C37H47Cl2N7O4S2 |
| Molecular Weight | 788.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Avatrombopag Impurity 60 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 788.85 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Avatrombopag Impurity 60 (CAS CATO-C4X-223460) is a certified pharmaceutical impurity reference standard with the molecular formula C37H47Cl2N7O4S2 and a molecular weight of 788.85 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avatrombopag Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C37H47Cl2N7O4S2 |
| Molecular Weight | 788.85 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag impurity 123 (CAS CATO-C4X-2234123)
- Avatrombopag Impurity 117 (CAS CATO-C4X-2234117)
- Avatrombopag Impurity 27 (CAS 3062079-49-3)
- Avatrombopag Impurity 103 (CAS CATO-C4X-2234103)
- Avatrombopag Impurity 80 (CAS CATO-C4X-223480)
- Avatrombopag Impurity 110 (CAS CATO-C4X-2234110)
- Avatrombopag Impurity 99 (CAS CATO-C4X-223499)
- Avatrombopag Impurity 113 (CAS CATO-C4X-2234113)
Recommended Standards
- (R)-(2,2',6,6'-Tetramethoxy-[3,3'-bipyridine]-4,4'-diyl)bis(bis(3,5-dimethylphenyl)phosphine oxide) (CAS 442905-30-8)
- Phalloidin (CAS 17466-45-4)
- N,N'-[(1S,2S)-1,2-Diphenyl-1,2-ethanediyl]bis[2-diphenylphosphinobenzamide] (CAS 143668-57-9)
- Dulcoside A (CAS 64432-06-0)
- Brivaracetam impurity 102 (CAS CATO-C4X-2007102)
- Tadalafil impurity 125 (CAS CATO-C4X-1087125)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
- 2,4-Dichloro-6-methylquinoline (CAS 102878-18-2)
- 6-Amino-1-butyl-5-{[(2-methoxyphenyl)methyl]amino}-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 571149-78-5)
- 2-Cyclopropyl-1-methyl-1H-imidazole-4-carboxylic acid (CAS 1403334-11-1)
- Amoxicillin Trimer Impurity 1 (CAS 174391-69-6)
- 5-Amino-N-ethyl-1H-pyrazole-1-carboxamide (CAS 154366-36-6)
- 3-Amino-2-(2-(diethylamino)thiazol-5-yl)-1,1,1-trifluoropropan-2-ol (CAS 1235439-98-1)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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