2-Cyclopropyl-2-(2,2,2-trifluoroacetamido)propanoic acid CAS 1177328-28-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1177328-28-7
Molecular FormulaC8H10F3NO3
Molecular Weight225.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Cyclopropyl-2-(2,2,2-trifluoroacetamido)propanoic acid CAS 1177328-28-7 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-Cyclopropyl-2-(2,2,2-trifluoroacetamido)propanoic acid (CAS 1177328-28-7) is a high-purity analytical reference standard with the molecular formula C8H10F3NO3 and a molecular weight of 225.17 g/mol.

Based on its molecular formula C8H10F3NO3, 2-Cyclopropyl-2-(2,2,2-trifluoroacetamido)propanoic acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 225.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H10F3NO3
Molecular Weight225.17 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms1

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