3-Chloro-6-(piperazin-1-yl)pyridazine dihydrochloride CAS 1177360-01-8
| CAS No. | 1177360-01-8 |
| Molecular Formula | C8H11ClN4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Chloro-6-(piperazin-1-yl)pyridazine dihydrochloride (CAS 1177360-01-8), a certified reference material (molecular formula C8H11ClN4HCl, MW 235.11 g/mol) for analytical method development and quality control.
3-Chloro-6-(piperazin-1-yl)pyridazine dihydrochloride (C8H11ClN4HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11ClN4 2*HCl |
| Molecular Weight | 235.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
- 9-Hydroxynonanal (CAS 22054-15-5)
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- Ethyl 1-((1,3-dioxoisoindolin-2-yl)methyl)-6,7-dimethoxyisoquinoline-4-carboxylate (CAS 264188-67-2)
- Abemaciclib Impurity 26 (CAS CATO-C4X-293726)
- 3-Bromo-6-chloropyridin-2(1H)-one (CAS 848423-85-8)
- 2-(dimethylamino)-2-phenylacetic acid hydrochloride (CAS 58685-78-2)
- 7-Methyl-2-thioxo-1,2-dihydroquinoline-3-carbaldehyde (CAS 880105-66-8)
- 1-Cyclopentylazetidin-3-ol (CAS 1201582-92-4)
- Liraglutide Impurity 21 TFA Salt (CAS CATO-C4X-199221)
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