Abemaciclib Impurity 26 CAS CATO-C4X-293726
| CAS No. | CATO-C4X-293726 |
| Molecular Formula | C11H12ClFN2 |
| Molecular Weight | 226.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Abemaciclib Impurity 26 (CAS CATO-C4X-293726) is a certified pharmaceutical impurity reference standard with the molecular formula C11H12ClFN2 and a molecular weight of 226.68 g/mol.
The molecular framework of Abemaciclib Impurity 26 (C11H12ClFN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Abemaciclib Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12ClFN2 |
| Molecular Weight | 226.68 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Abemaciclib Standards
- Abemaciclib Impurity 37 (CAS CATO-C4X-293737)
- Abemaciclib Impurity 53 (CAS CATO-C4X-293753)
- Abemaciclib impurity 118 (CAS CATO-C4X-2937118)
- Abemaciclib Impurity 91 (CAS 937605-75-9)
- Abemaciclib Impurity 175 (CAS CATO-C4X-2937175)
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- Abemaciclib Impurity 67 (CAS CATO-C4X-293767)
- Abemaciclib Impurity 83 (CAS 1508701-56-1)
Recommended Standards
- Methyl4-chlorobenzo[b]thiophene-2-carboxylate (CAS 35212-95-4)
- 4-Amino-5-(3-chlorophenyl)-4h-1,2,4-triazole-3-thiol (CAS 117320-66-8)
- 3-Chloro-4-methyl-1-benzothiophene-2-carboxylic acid 3287AF 923772-93-4 C10H7ClO2S (CAS 923772-93-4)
- 4-Amino-5-(2-chlorophenyl)-4H-1,2,4-triazole-3-thiol (CAS 13229-02-2)
- Ibuprofen Impurity 156 (CAS CATO-C4X-1082156)
- Bicalutamide EP Impurity L (CAS 2711603-77-7)
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- 7-(methoxymethyl)-1,3,5-trimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine (CAS 2627592-44-1)
- 2-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one (CAS 2034-61-9)
- 3,6-Dimethylimidazo[1,2-c]pyrimidin-5(6H)-one (CAS 57491-48-2)
- N-methyl-1-(1-methyl-3-phenyl-1H-pyrazol-4-yl)methanamine (CAS 1216004-18-0)
- Semaglutide Impurity 150 xTFA (CAS CATO-C4X-2226150)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com