(R)-6,6’-Dibromo-2,2’-dimethoxy-1,1’-binaphthalene CAS 117745-45-6
| CAS No. | 117745-45-6 |
| Molecular Formula | C22H16Br2O2 |
| Molecular Weight | 472.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-6,6’-Dibromo-2,2’-dimethoxy-1,1’-binaphthalene (CAS 117745-45-6) is a high-purity analytical reference standard with the molecular formula C22H16Br2O2 and a molecular weight of 472.17 g/mol.
The molecular framework of (R)-6,6’-Dibromo-2,2’-dimethoxy-1,1’-binaphthalene (C22H16Br2O2) is characterized by a steroid core, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16Br2O2 |
| Molecular Weight | 472.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
Related R Standards
- (S)-6,6’-Dibromo-2,2’-dimethoxy-1,1’-binaphthalene (CAS 117745-41-2)
- (R)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl (CAS 75714-59-9)
- (S)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl (CAS 75714-60-2)
- 3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthalene (CAS 75640-69-6)
- 6,8-Dibromo-3-(3,4-dimethylbenzenesulfonyl)-2H-chromen-2-one (CAS 866013-15-2)
- 4-((3,5-Dibromo-2-hydroxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 676336-51-9)
- 4-((3,5-Dibromo-2-hydroxybenzylidene)amino)-3-(4-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 577695-15-9)
- 4,4"-Dibromo-2,2',2",5,5',5"-hexamethyl-1,1':4',1"-terphenyl (CAS 1382735-12-7)
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