1-(4-(2-Chloro-4-fluorophenoxy)phenyl)ethan-1-ol CAS 1178039-67-2
| CAS No. | 1178039-67-2 |
| Molecular Formula | C14H12ClFO2 |
| Molecular Weight | 266.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-(2-Chloro-4-fluorophenoxy)phenyl)ethan-1-ol.
CATO supplies 1-(4-(2-Chloro-4-fluorophenoxy)phenyl)ethan-1-ol (CAS 1178039-67-2), a certified reference material (molecular formula C14H12ClFO2, MW 266.70 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system, 1-(4-(2-Chloro-4-fluorophenoxy)phenyl)ethan-1-ol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 266.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12ClFO2 |
| Molecular Weight | 266.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-[(4-chloro-3,5-dimethyl-1h-pyrazol-1-yl)methanesulfonyl]acetic acid (CAS 1006319-32-9)
- 5-Chloro-1-(2-fluorophenyl)-3-(propan-2-yl)-1H-pyrazole-4-carbaldehyde (CAS 1152576-41-4)
- 5-Chloro-1-(4-fluorophenyl)-3-(propan-2-yl)-1H-pyrazole-4-carbaldehyde (CAS 1152960-71-8)
- 5-Chloro-1-(2-fluorophenyl)-3-propyl-1H-pyrazole-4-carbaldehyde (CAS 1152977-25-7)
- 5-Chloro-1-(4-fluorophenyl)-3-propyl-1H-pyrazole-4-carbaldehyde (CAS 1152977-66-6)
- 5-Chloro-1-(3-fluorophenyl)-3-propyl-1H-pyrazole-4-carbaldehyde (CAS 1192999-22-6)
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Recommended Standards
- 1-(2-(4-Chlorophenoxy)-5-fluorophenyl)ethan-1-ol (CAS 1156736-57-0)
- 6-((2-Chlorophenyl)thio)pyridazine-3-carboxylic acid (CAS 1183813-48-0)
- Methyl 5-(chlorosulfonyl)-1-isopropyl-1h-pyrazole-3-carboxylate (CAS 1260658-86-3)
- 5-Chloro-1-(3-fluorophenyl)-3-(propan-2-yl)-1H-pyrazole-4-carbaldehyde (CAS 1275049-06-3)
- n-Butyl-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1019544-62-7)
- 3-Bromo-2-chloro-6-fluoroaniline, n-boc protected (CAS 1820673-55-9)
- 2,2',4'-Trifluoro-[1,1'-biphenyl]-4-carboxylic acid (CAS 1261950-00-8)
- 8-Methyl-4-(2-phenylbutanoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326812-71-8)
- 4-Bromo-3-(ethoxymethyl)benzonitrile (CAS 837408-81-8)
- Testosterone Impurity 48 (CAS 2602-86-0)
- 2-(2-Hydroxycyclohexyl)acetonitrile (CAS 90242-33-4)
- (2-Bromophenyl)(4-methoxy-3,5-dimethylphenyl)methanol (CAS 1443312-97-7)
- Benzyl 5-Methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate (CAS 913376-49-5)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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