3-Hydroxy-N-(1-(thiophen-2-yl)ethyl)picolinamide CAS 1179216-95-5
| CAS No. | 1179216-95-5 |
| Molecular Formula | C12H12N2O2S |
| Molecular Weight | 248.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Hydroxy-N-(1-(thiophen-2-yl)ethyl)picolinamide (C12H12N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-Hydroxy-N-(1-(thiophen-2-yl)ethyl)picolinamide (CAS 1179216-95-5), a certified reference material (molecular formula C12H12N2O2S, MW 248.30 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O2S |
| Molecular Weight | 248.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Hydroxy Standards
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Recommended Standards
- 1-(Azetidin-1-ylsulfonyl)piperidine-3-carboxylic acid (CAS 1178494-27-3)
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- N-(2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl)benzamide (CAS 1199215-56-9)
- 6-Bromo-4-chloro-5-(difluoromethyl)picolinaldehyde (CAS 1804656-47-0)
- 2-(3,5-Dimethyl-1H-pyrazole-1-carbonyl)-N-methyl-N,4-bis(4-methylphenyl)thiophene-3-sulfonamide (CAS 1173751-96-6)
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- 4-(Methylsulfonyl)phenylhydrazine Hydrochloride (CAS 17852-67-4)
- 1-(4-(Benzyl(methyl)amino)but-2-yn-1-yl)-3-cyclohexylurea (CAS 1396680-04-8)
- (5-Fluoro-1H-pyrazol-3-yl)methyl nicotinate (CAS 23723-16-2)
- (5-chloro-3-methyl-thieno[2,3-c]pyridin-2-yl)methanol (CAS 1268834-51-0)
- 2-Amino-N-methoxy-N-methylbenzenesulfonamide (CAS 1156154-52-7)
- (R)-1-(4-(Methylthio)phenyl)ethan-1-amine (CAS 1217456-30-8)
- Semaglutide Impurity 246 (CAS CATO-C4X-2226246)
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