[1-(2,2-difluoroethyl)pyrrolidin-2-yl]methanamine CAS 1179299-77-4
| CAS No. | 1179299-77-4 |
| Molecular Formula | C7H14F2N2 |
| Molecular Weight | 164.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of [1-(2,2-difluoroethyl)pyrrolidin-2-yl]methanamine (C7H14F2N2) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
[1-(2,2-difluoroethyl)pyrrolidin-2-yl]methanamine (CAS 1179299-77-4) is a high-purity analytical reference standard with the molecular formula C7H14F2N2 and a molecular weight of 164.20 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), [1-(2,2-difluoroethyl)pyrrolidin-2-yl]methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H14F2N2 |
| Molecular Weight | 164.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related difluoroethyl Standards
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- 1-(2,2-Difluoroethyl)-1,4-diazepane (CAS 1182782-23-5)
- 2-(1,1-difluoroethyl)pyridin-4-amine (CAS 1211586-93-4)
- N-(2,2-difluoroethyl)piperidin-4-amine (CAS 1378792-60-9)
- [2-(2,2-Difluoroethyl)pyrrolidin-2-yl]methanamine (CAS 1638763-27-5)
- 4-(2,2-Difluoroethyl)piperidin-4-amine (CAS 1889878-41-4)
- 4-(1,1-Difluoroethyl)cyclohexan-1-ol (CAS 1379340-14-3)
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- N-(Piperidin-1-yl)-4-(trifluoromethyl)-pyridin-2-amine (CAS 1547728-90-4)
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