N-(2,2-difluoroethyl)piperidin-4-amine CAS 1378792-60-9
| CAS No. | 1378792-60-9 |
| Molecular Formula | C7H14F2N2 |
| Molecular Weight | 164.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(2,2-difluoroethyl)piperidin-4-amine (CAS 1378792-60-9), molecular formula C7H14F2N2 and molecular weight 164.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2,2-difluoroethyl)piperidin-4-amine (C7H14F2N2) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), N-(2,2-difluoroethyl)piperidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H14F2N2 |
| Molecular Weight | 164.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 1-(2,2-Difluoroethyl)piperidin-4-amine (CAS 1119499-74-9)
- [1-(2,2-difluoroethyl)pyrrolidin-2-yl]methanamine (CAS 1179299-77-4)
- 1-(2,2-Difluoroethyl)-1,4-diazepane (CAS 1182782-23-5)
- 2-(1,1-difluoroethyl)pyridin-4-amine (CAS 1211586-93-4)
- [2-(2,2-Difluoroethyl)pyrrolidin-2-yl]methanamine (CAS 1638763-27-5)
- 4-(2,2-Difluoroethyl)piperidin-4-amine (CAS 1889878-41-4)
- 4-(1,1-Difluoroethyl)cyclohexan-1-ol (CAS 1379340-14-3)
- 2-(2,2-Difluoroethyl)cyclohexan-1-ol (CAS 1511034-03-9)
Recommended Standards
- (5,6,7,8-Tetrahydroquinazolin-2-yl)methanol (CAS 1378665-98-5)
- 6-Amino-5,6,7,8-tetrahydroquinolin-2(1H)-one (CAS 1378994-39-8)
- 3-Amino-5,6,7,8-tetrahydroquinolin-5-ol (CAS 1378259-92-7)
- 4-(Oxetan-3-yl)benzene-1,2-diamine (CAS 1380292-62-5)
- 1-(4-Fluoro-benzenesulfonyl)-piperidin-4-ylamine (CAS 790201-74-0)
- 5-(1H-[1,2,4]Triazol-3-ylsulfanyl)-furan-2-carbaldehyde hydrochloride (CAS 1185295-29-7)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)propan-2-ol (CAS 163557-41-3)
- 2,3-Dichloro-6-fluoroaniline (CAS 1017777-51-3)
- Methyl 2-[4-(4-chloro-2-methoxyphenyl)phenyl]acetate (CAS 1820664-73-0)
- n-(1-Cyclopropylethyl)-4-(methylthio)aniline (CAS 1019586-26-5)
- (1S,6R,7R,8R,8aS)-octahydroindolizine-1,6,7,8-tetraol (CAS 106798-21-0)
- 3-(2,3-Dihydro-5-indenyl)propionic Acid (CAS 23291-98-7)
- 2-Bromo-5-cyano-4-nitrobenzenesulfonyl chloride (CAS 1805190-38-8)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
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